Our lab studies molecular and cellular mechanisms that are dictated by the extracellular environment after vascular damage and regulate degenerative and repair processes upon injury or disease. Our current research focuses on identifying the molecular and cellular interface that fibrin utilizes to interact with nervous system cells and change their functions. Our ultimate goal is to use these interactions in a therapeutic manner for tissue repair and regeneration. We integrate animal modeling, histopathology, microscopy, tissue culture and biochemistry techniques, as a multifaceted experimental approach to address the biological complexity of disease and repair mechanisms.