PUBLICATIONS

References from PubMed
Link

1. Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K,. 2007. The fibrin-derived ?377-395 peptide inhibits microglia activation and reverses relapsing paralysis in central nervous system autoimmune disease. J Exp Med, in press.

2. Arthur DB, Akassoglou K, Insel PA. 2006. P2Y2 and TrkA receptors interact with Src family kinase for neuronal differentiation. Biochem. Biophys. Res. Commun. 347:678-82.

3. Arthur DB, Georgi S, Akassoglou K, Insel PA. 2006. Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival. J. Neurosci. 26:3798-3804

4. Arthur DB, Akassoglou K,*, Insel PA*. 2005. P2Y2 Receptor Activates NGF/TrkA Receptor Signaling to Enhance Neuronal Differentiation. Proc Natl Acad Sci USA 102:19138-43. *These authors contributed equally to this work.

5. Akassoglou K,. 2005. Nerve growth factor – independent neuronal survival. A role for NO donors. Mol. Pharmacol. 68:952-955.

6. Adams, R. A., Passino M, Sachs B, Nuriel T, Akassoglou K,. 2004. Fibrin mechanisms and functions in nervous system pathology. Mol. Interven. 4:163-176. Invited Review

7. Akassoglou K, Adams, R. A., Bauer J, Mercado P, Tseveleki V, Lassmann H, Probert L and Strickland S. 2004. Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis. Proc Natl Acad Sci USA 101:6698-6703.

8. Akassoglou K, Malester B, Xu J, Tessarollo L, Rosenbluth J, Chao MV. 2004. Brain-specific deletion of Neuropathy Target Esterase/Swiss cheese results in neurodegeneration. 2004. Proc Natl Acad Sci USA101:5075-5080.

9. Akassoglou K, Akpinar P, Murray S, Strickland S. 2003. Fibrin is a regulator of Schwann cell migration after sciatic nerve injury. Neurosci Lett. 338:185-188.

10. Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, and Probert L. 2003. Transmembrane TNF signaling through the p75 TNFR induces ischaemia in the CNS of transgenic mice. Proc Natl Acad Sci USA 100:709-714.

11. Akassoglou K,., Yu W-M, Akpinar P, Strickland S. 2002. Fibrin inhibits peripheral nerve regeneration by arresting Schwann cell differentiation. Neuron,33: 861-875.

12. Akassoglou K, Strickland S. 2002. Nervous system pathologies: The fibrin perspective. Biol Chem, 383:37-45.

13. Probert L, Akassoglou K,. 2001. Glial expression of cytokines in transgenic animals- how do these models reflect the "normal situation”. Glia, 36:212-219.

14. Brodsky S, Chen J, Lee A, Akassoglou K, Goligorsky MS. 2001. Plasminogen-dependent and –independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis. Am J Physiol Heart Circ Physiol, 281:H1784-792.

15. Probert L, Eugster HP, Akassoglou K, Bauer J, Frei K, Lassmann H, Fontana A. 2000. TNFR1 signaling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain 123:2005-2019.

16. Akassoglou K, Kombrink KW, Degen JL, Strickland S. 2000. Tissue plasminogen activator-mediated fibrinolysis protects from axonal demyelination after sciatic nerve injury, J Cell Biol, 149:1157-1166.

17. Akassoglou K, Bauer J, Kassiotis G, Lassmann H, Kollias G, Probert L. 1999. Transgenic models of TNF induced demyelination. Adv Exp Med Biol 468:245-259.

18. Aloe L, Properzi F, Probert L, Akassoglou K, Kassiotis G, Micera A, Fiore M. 1999. Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal. Brain Res. 840: 125-137.

19. Kassiotis G, Bauer J, Akassoglou K, Lassmann H, Kollias G, and Probert L. 1999. A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice. Eur J Immunol 29:912-917.

20. Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G and Probert L. 1998. Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the CNS of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Am J Pathol 153:801-813.

21. Probert L, Akassoglou K, Kassiotis G, Pasparakis M, Alexopoulou L and Kollias G. 1997. TNFa transgenic and knock out models of CNS inflammation and degeneration. J Neuroimmunol 72:137-141.

22. Akassoglou K, Probert L, Kontogeorgos G and Kollias G. 1997. Astrocyte, but not neuron-specific, transmembrane TNF triggers inflammation and degeneration in the CNS of transgenic mice. J Immunol 158:438-445.

23. Douni E, Akassoglou K, Alexopoulou L, Georgopoulos S, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D, Probert L and Kollias G. 1996. Transgenic and knock out analysis of the role of TNF in immune regulation and disease pathogenesis. J Inflamm 47:27-38.

24. Fiore M, Probert L, Kollias G, Akassoglou K, Alleva E and Aloe L. 1996. Neuro-behavioral alterations in developing transgenic mice expressing TNF-a in the brain.Brain Behav Immun 10:126-138.

25. Probert L, Akassoglou K, Alexopoulou L, Douni E, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D and Kollias G. 1995. Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice. J Leukoc Biol 59:518-525.

26. Probert L, Akassoglou K, Pasparakis M, Kontogeorgos G and Kollias G. 1995. Spontaneous inflammatory and demyelinating disease in transgenic mice showing central nervous system-specific tumor necrosis factor a expression. Proc Natl Acad Sci USA 92:11294-11298.

Book Chapter

1.   Akassoglou K,, Kassiotis G, Kollias G, Probert L. Role for TNF in CNS inflammation, demyelination and neurodegeneration studied in transgenic mice, in Neuroimmunodegeneration Edited by P. Wong, B. Lynn, LANDES Bioscience, 1998, pp. 133-149.