References from PubMed

Selected Publications

Regulation of hepatic stellate cell differentiation by the neurotrophins receptor p75NTR. Passino MA, Adams RA, Sikorski SL, Akassoglou K. 2007. Science, 315(5820):1853-6. Editor’s Choice SKTE.

The fibrin-derived y377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease. Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, and Akassoglou K. 2007. J Exp Med doi:10.1084/jem.20061931 . PDF

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P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation. Arthur DB, Akassoglou K, Insel PA. 2005. Proc Natl Acad Sci USA 102:19138-43.

Nerve growth factor-independent neuronal survival: a role for NO donors. Akassoglou K. 2005. Mol Pharmacol 68:952-5.

Fibrin mechanisms and functions in nervous system pathology. Adams, R. A., Passino M., Sachs, B.D., Nuriel T., Akassoglou K.         2004. Mol Interv 4:163-176. PDF

Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis. Akassoglou K, Adams, R, Bauer J, Mercado P, Tseveleki V, Lassmann H, Probert L and Strickland S. 2004. Proc Natl Acad Sci USA 101:6698-6703. PDF

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Transmembrane TNF signaling through the p75 TNFR induces ischaemia in the CNS of transgenic mice. Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, and Probert L. 2003. Proc Natl Acad Sci USA 100:709-714. PDF

Fibrin inhibits peripheral nerve regeneration by arresting Schwann cell differentiation. Akassoglou K, Yu W-M, Akpinar P, Strickland S. 2002. Neuron 33: 861-875. PDF

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Nervous system pathologies: The fibrin perspective.Akassoglou K, Strickland S. 2002. Biol Chem 383:37-45. PDF)

Tissue plasminogen activator-mediated fibrinolysis protects from axonal demyelination after sciatic nerve injury. Akassoglou K, Kombrink KW, Degen JL, Strickland S. 2000. J Cell Biol, 149:1157-1166. PDF

Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the CNS of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G and Probert L. 1998. Am J Pathol 153:801-813. PDF